The #1 Intervention Bryan Johnson Swears By

CChris Williamson
DermatologyWeight Loss/NutritionMental HealthBeautyConsumer Electronics

Transcript

00:00:00HBOT talked to me about that.
00:00:01I was messaging you the day that I started my HBOT
00:00:05was the day that you put your video out.
00:00:06And I'm in there and you were like,
00:00:08I can't remember what the fuck you,
00:00:09you replied with 20 and five,
00:00:1483% with natural blah, blah, blah.
00:00:19'Cause I'm in this big fucking metal dildo
00:00:21and the guy that's there, Vance,
00:00:23from Beam Hyperbarics in Austin,
00:00:25if anyone wants to go to a great hyperbarics place,
00:00:27it's fucking sick and bucket by the hour, Vance is great.
00:00:29And I'm like knocking on the little,
00:00:32this tiny little portal out of my submarine
00:00:35and he comes in and I just showed my phone.
00:00:38I'm like, what's that?
00:00:40I couldn't be bothered to use the radio to get outside.
00:00:42I'm like, Brian, Brian messaged you.
00:00:44Are we doing this?
00:00:45And you sort of went.
00:00:46- That's so funny.
00:00:48- Yeah, put his thumb up like that.
00:00:49So hyperbaric red pill me.
00:00:53- When you messaged me, I was worried about you
00:00:55because a week before somebody had blown up in Arizona.
00:01:00So yeah.
00:01:01- What does that look like?
00:01:02- Well, so in hyperbaric, the idea is you pressurize.
00:01:07So you're actually, so at atmosphere at sea level,
00:01:11we're about 15 pounds per square inch of concentration
00:01:16of oxygen at two atmospheres or 30.
00:01:19So you pressurize and some hyperbaric chambers,
00:01:23they pressurize and then they just push
00:01:25100% oxygen into the chamber.
00:01:28So you're just hanging out and breathing the oxygen.
00:01:30But if you're doing that,
00:01:31you're sitting in a pressurized chamber
00:01:33and you're basically a flammable.
00:01:35By a bomb.
00:01:37- You're a candleweight.
00:01:38- You're a bomb.
00:01:39So if something, if there's a spark of any type,
00:01:42you just blow up.
00:01:43- Your phone or some device that you've got with you
00:01:46or whatever the fuck.
00:01:47Okay, no, no, no, no, no.
00:01:49This was, I was not, I had the,
00:01:53I was breathing the mask.
00:01:53I was doing stuff.
00:01:54- Cool, great.
00:01:55Okay, cool, yeah.
00:01:56So yes, hyperbaric oxygen therapy,
00:01:58I think today it's fair to say has been
00:02:01the single best performing therapy we've ever done.
00:02:05And this is both good news and bad news
00:02:08because the bad news is that it's expensive,
00:02:10it's inaccessible, it's time consuming.
00:02:12- Super inconvenient.
00:02:13- So it sucks because I hate sharing this
00:02:15because people, it's very exciting,
00:02:17but then it sucks because people can't do it.
00:02:19- I mean, if you're already to say,
00:02:21I've got to find a sauna to use
00:02:23and most people don't have a sauna in the house.
00:02:25Oh God, now you tell me I need to produce my own oxygen.
00:02:28This thing weighs fucking two tons.
00:02:31I don't, where does it fit?
00:02:32- Totally, yeah.
00:02:33And like who has 90 minutes in a day to go do this thing?
00:02:37So I would just say for people who have a serious condition
00:02:42and there's a variety of conditions that this could address,
00:02:46like even cognitive decline or, you know,
00:02:50wounds for diabetes.
00:02:51- What would be on the list?
00:02:52- Like, so there's a lot of emergent evidence
00:02:55for a cognitive decline that if you're entering
00:02:58the latter parts of your life and you're really struggling,
00:03:01this could have a meaningful impact on that.
00:03:03It is used for diabetics who can't heal very well.
00:03:06It's used for healing.
00:03:07So people who've had surgeries
00:03:09to accelerate the healing process.
00:03:10If you have some kind of injury,
00:03:11you're really trying to overcome, that can be great.
00:03:13So like there are some--
00:03:14- It's telling me that some athletes post surgery
00:03:15are in 90 minutes, three times a day.
00:03:17- Exactly.
00:03:18- They're trying to hit that 90 session number within weeks.
00:03:22- Yes.
00:03:23So like there are some specialized applications where,
00:03:25and people where it makes sense for the person to do,
00:03:28but I just want to be very sensitive.
00:03:29I understand like it sucks to hear
00:03:32something's really efficacious
00:03:33and you can't get out of exclusion.
00:03:34Yeah, it makes sense.
00:03:35So like, but yeah, we basically, like we do with all things,
00:03:38we measured, we had this, we cast this really wide net.
00:03:41We measured everything we could.
00:03:42My brain, my microbiome, a full blood panel, saliva stool,
00:03:48metabolomics, proteomics, like you name it, we measured it.
00:03:50And we just found improvements across the board.
00:03:53It was really, because most therapies will improve
00:03:56like this particular marker or that marker,
00:03:58but rarely do they have this broad spectrum improvement.
00:04:02So we saw like the cognitive decline marker,
00:04:06PTAL217 drop, we saw a microbiome.
00:04:08I had zero dysbiosis in my microbiome,
00:04:11like no signatures at all of dysbiosis.
00:04:15We saw, I had no detectable inflammation in my body.
00:04:17So like when my HSCRP came back, zero.
00:04:20- The 99.99, like he's beaten the test.
00:04:23- Exactly, it was really remarkable across the board.
00:04:26And so it was really efficacious.
00:04:27I did 60 sessions over 90 days and I've continued to do it.
00:04:31I've now done something like 200 sessions
00:04:34over the past year or something like that.
00:04:36So I just have it as part of my routine.
00:04:38I do it, you want to be careful not to do it too much
00:04:41because you'll have oxygen toxicity.
00:04:44- Yes.
00:04:44- You want to have some-
00:04:45- But that's why the five minute break is so important, right?
00:04:46- Yeah, and I also take like a week long break.
00:04:48I'll do a sprint, then a week long break.
00:04:50So you just need to be careful
00:04:51'cause you can overdo it and cause harm.
00:04:53- What was the protocol of mask on, mask off?
00:04:56- 20 minutes on, five minutes off.
00:04:58- Cool, yeah, I was doing that.
00:05:00The one super fucking annoying thing there is
00:05:04it's very relaxing to be in,
00:05:06it can be very relaxing once you've pressurized,
00:05:09but you can't sleep.
00:05:11- Yeah, exactly, you're busy.
00:05:13- Gotta take this thing on and off.
00:05:16- One of the things that I really enjoyed doing
00:05:19was HIV resonance breathing while I was in there.
00:05:21Have you got into resonance breathing yet?
00:05:23Have you been doing it in the H-bot?
00:05:24- Yes.
00:05:25- So much fun.
00:05:26- Yeah, it is.
00:05:27- So much fun.
00:05:28There's a product that I got sent,
00:05:31I think in the first person outside of the company
00:05:33to have got it, it's this little lamp.
00:05:34I wouldn't be able to take it in,
00:05:35it would all fucking hell would break loose,
00:05:37but it's basically a resonance breathing stone
00:05:40and you pick it up and it's got an FDA approved thing in it
00:05:43and the lamp goes up and down and you put it back
00:05:44and it's done.
00:05:45So you don't need your phone,
00:05:46so it's brilliant.
00:05:47But elite HRV is what I was using with the strap.
00:05:50I'm gonna guess you'll have seen.
00:05:51One thing that I noticed about that,
00:05:53it's a niche issue.
00:05:56The strap that came with the elite HRV thing,
00:06:00which you put on so that it can detect
00:06:01like real high fidelity, high Hertz heart rate thing.
00:06:06The button that you use to press to turn it on
00:06:09has a tiny little air pocket around it.
00:06:11So I got into the fucking H-bot
00:06:14and by the time I'd pressurized to get down there,
00:06:16the button had been smashed and I couldn't press,
00:06:18there was no air to press the button.
00:06:21And then I was like trying to press it
00:06:23and it's just like SpongeBob when he gets outside
00:06:26of the water.
00:06:27So anyway, H-bot, so I mean a couple of questions on this.
00:06:3260 sessions as quickly as possible, basically,
00:06:36to start to accumulate.
00:06:39'Cause it's not like a one and done type of thing.
00:06:42I think I asked you this at the time.
00:06:45I'm interested if there's any more information.
00:06:48Going from state change to trait change,
00:06:52is this the sort of thing that locks in?
00:06:55I'm aware you haven't then tested coming off
00:06:57and seeing what the tail of this is.
00:07:00But the same thing goes for sauna.
00:07:02Are you just fighting entropy with this?
00:07:05Is it something that you just need to do?
00:07:06Or is there any, 'cause I think there's a,
00:07:09I certainly know in me, if I look at a therapy
00:07:11or a modality or whatever,
00:07:13and I find that there's no carryover,
00:07:18I feel despondent, 'cause I'm like, fucking hell,
00:07:21like I've just found this new thing.
00:07:22Here's another thing I have to do.
00:07:25Does that make sense?
00:07:26- Yeah, yeah, yeah.
00:07:26It's because both you and I are on the other side
00:07:29of the entropy curve.
00:07:31The dealer you want is youth, right?
00:07:34Like when you're 12, you just keep on getting better.
00:07:38But once you cross over to your--
00:07:39- Slow down, slow down.
00:07:41- Exactly.
00:07:42They just, every day they get up and shit's just better.
00:07:45But yeah, you and I are both on the other side
00:07:47where we're on this irreversible decline.
00:07:49And so yes, you've got to keep it up.
00:07:51But one thing people are not aware of with HBOT
00:07:53is it's the best skin rejuvenation therapy in the world.
00:07:57So a lot of people-- - Better than red light,
00:07:59better than microneedling.
00:08:00- Everything.
00:08:01Better than the vampire facials, better than any laser.
00:08:03It is because if you look at the data on the biopsies
00:08:07of rebuilding collagen, elastin, and reducing senescent cell,
00:08:11it basically remodels your entire skin.
00:08:14It's not just face.
00:08:15Every layer of skin you're remodeling is really remarkable.
00:08:19If you look at people, if I see people now,
00:08:22I can tell a signature of HBOT skin.
00:08:26It's very, very clear to me what it looks like.
00:08:29And so it just, it happens.
00:08:31So yeah, that's the other thing is a lot of women
00:08:34who really care a lot about skin, HBOT--
00:08:37- Getting the fucking HBOT.
00:08:38- Then you, if you pair, like the best banger protocol
00:08:42is to, for skin, is to pair the best devices with HBOT.
00:08:47So you basically, you do like a surface level,
00:08:50like a 1550 nanometer to resurface the skin
00:08:52for like spots, wrinkles, stuff like that.
00:08:54Then you do HBOT and you can accelerate the healing.
00:08:56- Is that microneedling?
00:08:57Is that what you're referring?
00:08:58- No, it's just a laser.
00:08:59Like a 1550 nanometer laser where it's like,
00:09:01it's a very benign laser if you do it right.
00:09:05It has lower risk of like pigmentation issues.
00:09:09For wrinkles, spots, just like for texture.
00:09:12And then you can do a deeper device,
00:09:14like a softwave, S-O-F-W-A-V-E,
00:09:16where it's ultrasound, where it's 1.5 milliliters below,
00:09:20millimeters below the dermis.
00:09:21So you hit top layer and underneath the dermis.
00:09:23So you're rebuilding collagen
00:09:25and the entire scaffolding of the skin.
00:09:27And then you do the HBOT and then you accelerate the healing.
00:09:30So you basically do more sessions in this, yeah.
00:09:33So that's like--
00:09:34- You do an acute like skin rejuvenation thing
00:09:36and then fuck up.
00:09:37Kena, are you still here?
00:09:38She's outside.
00:09:40I think I did softwave
00:09:41'cause I went to your dermatologist in LA.
00:09:44- Which one?
00:09:45- Fuck, I can't remember the lady's name.
00:09:46It was in, that was why I had a mustache.
00:09:48I grew a mustache 'cause I needed to get rid
00:09:50of my facial hair because they needed to do that
00:09:52in order to be able to, I'm pretty,
00:09:53I'm almost certain it was softwave that I was doing.
00:09:56- Was it like, it felt like a--
00:09:59- Cigarette burn that never actually got to a bone.
00:10:01- Exactly.
00:10:02Yeah, like you're being singed by like a hot metal iron.
00:10:06- Yeah, but it never actually peaks to the,
00:10:09it was a really interesting lesson in,
00:10:12and the, blowing the cold shit, yeah, yeah, yeah.
00:10:15It was a really interesting lesson in pain that
00:10:20because what you realize is you ride this crescendo
00:10:25for the people that haven't seen it.
00:10:26It's literally as if someone was to put something really hot
00:10:28out on you and when that happens, there is a swelling,
00:10:31there is a crescendo, but it usually peaks
00:10:33that you can almost hear it, right?
00:10:35If you ever put alcohol on an open wound, that's--
00:10:37- Yeah.
00:10:38- It goes like that.
00:10:40But it doesn't ever get above a six or so.
00:10:44- So if she did, if she set the settings to 3.5 joules,
00:10:49which is the lowest setting, then it gets pretty tolerable.
00:10:52If she goes to 4.2 top end,
00:10:54'cause basically it's a total energy per area.
00:10:57- I think I had it at around about three point,
00:11:00I think she had it at 3.6, 3.7, so I was being a weenie.
00:11:03- Okay, yeah, so if you have the 4.2,
00:11:05where it basically like it cuts down the number of pulses
00:11:07by 30%, if you want to like zip through it,
00:11:09God damn that, that is so painful.
00:11:11- No, thank you.
00:11:12- Oh man, it does, it just feels like a red, hot iron.
00:11:17- I'm all right, I'm all right, no more, thank you.
00:11:20A quick aside, if you have been feeling a bit sluggish,
00:11:22your testosterone levels might be the problem.
00:11:24They play a huge role in your energy, your focus,
00:11:26and your performance, but most people have no idea
00:11:28where those are or what to do if something's off,
00:11:31which is why I partnered with function
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00:11:55And unfortunately, getting your blood work drawn
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00:12:15That's functionhealth.com/modernwisdom.
00:12:19Thank you very much for tuning in.
00:12:21If you enjoyed that clip, the full episode
00:12:23in all of its glory, waiting for you.
00:12:26Right here.
00:12:29- Go on, press it.

Key Takeaway

Bryan Johnson advocates for Hyperbaric Oxygen Therapy as a premier longevity tool that offers systemic health benefits and unparalleled skin rejuvenation, despite its high cost and time requirements.

Highlights

Hyperbaric Oxygen Therapy (HBOT) is identified as the single best-performing therapy among the many interventions Bryan Johnson has tested.

The therapy showed broad-spectrum improvements across brain health, inflammation markers, and the microbiome, specifically dropping the cognitive decline marker PTAL217.

Safety is a critical concern as 100% oxygen environments can be flammable; Johnson recommends a mask-based protocol (20 minutes on, 5 minutes off) to avoid oxygen toxicity.

HBOT is described as the world's best skin rejuvenation therapy, outperforming lasers and microneedling by remodeling collagen and elastin throughout the entire body.

The intervention is highly resource-intensive, requiring specialized equipment, significant time (90-minute sessions), and substantial financial investment.

Combining HBOT with specific dermatological treatments like 1550nm lasers or Softwave ultrasound can accelerate healing and maximize aesthetic results.

Timeline

Introduction to HBOT and Safety Precautions

The speakers begin by discussing the practical experience of being inside a hyperbaric chamber, which they humorously compare to a metal dildo or a small submarine. Bryan Johnson explains the mechanics of the therapy, noting that at sea level, we experience 15 pounds per square inch of pressure, while the chamber can double that. He highlights a major safety risk where some chambers fill the entire space with 100% oxygen, essentially turning the patient into a flammable 'bomb' if a spark occurs. To mitigate this risk, Johnson uses a specific mask-based delivery system while inside the pressurized environment. This section emphasizes the importance of professional supervision and proper equipment when pursuing such an intense medical intervention.

Systemic Benefits and Accessibility Challenges

Johnson describes HBOT as the most efficacious therapy he has ever measured, showing improvements across nearly every biomarker tested. While most treatments only move one or two markers, HBOT resulted in zero detectable inflammation (HSCRP) and a complete lack of dysbiosis in his microbiome. He acknowledges the 'bad news' that the therapy is expensive, time-consuming, and inaccessible for the average person, often requiring 90 minutes per day. Despite these barriers, it shows immense promise for treating cognitive decline, diabetic wounds, and surgical recovery. Johnson's personal protocol involved 60 sessions over 90 days, eventually totaling over 200 sessions in a single year.

Optimizing the Protocol and HRV Breathing

The conversation shifts to the specific protocol of 20 minutes with the oxygen mask on followed by 5 minutes off to prevent oxygen toxicity. Johnson mentions that he takes week-long breaks between intensive 'sprints' of therapy to ensure the body isn't overtaxed. The speakers also discuss the benefits of practicing Heart Rate Variability (HRV) resonance breathing while inside the chamber to enhance relaxation. They share a humorous anecdote about how the pressure inside the chamber can actually crush air pockets in electronic devices, making them unusable. This segment underscores the transition from 'state changes' to long-term 'trait changes' in the pursuit of reversing the entropy of aging.

Skin Rejuvenation and Advanced Aesthetic Pairings

Johnson makes the bold claim that HBOT is the best skin rejuvenation therapy in existence, even surpassing red light and vampire facials. By biopsies, the therapy is shown to rebuild collagen and elastin while reducing senescent cells across the entire body, not just the face. He suggests a 'banger protocol' that pairs HBOT with a 1550 nanometer laser for surface texture and 'Softwave' ultrasound for deep dermis remodeling. The speakers describe the intense pain of these laser treatments, comparing it to being singed by a hot metal iron or a cigarette burn. However, they note that the accelerated healing provided by HBOT makes these aggressive aesthetic procedures much more effective.

Health Monitoring and Conclusion

The video concludes with a sponsored segment regarding Function Health, a service that monitors over 100 biomarkers including testosterone. The host emphasizes that understanding what is happening inside the body is crucial for anyone following high-level longevity protocols like those discussed. He highlights the cost-effectiveness of this comprehensive blood work compared to traditional lab tests. The speaker encourages viewers to take actionable steps toward improving their lifespan through data-driven insights. Finally, the host invites the audience to watch the full episode for more in-depth discussion on these longevity interventions.

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